Figure 2 - full size

Figure 2.
Figure 2. Ribbon diagram of the DEP domains of Epac and Dishevelled. The DEP domains of Epac (yellow and green) and Dishevelled (gray) are superimposed on each other. Secondary structure elements are labeled as in Fig. 1c. N and C termini, as well as the position of the residues forming the dipole, are indicated as follows: '1' corresponds to Asp225^Epac and Glu448^Dvl1; '2' to Glu222^Epac and Asp445^Dvl1; and '3' to Lys212^Epac and Lys434^Dvl1.