Figure 2 - full size

Figure 2.
Figure 2. (a) Structure of the Impa(70-529)-SV40 NLS complex. Importin-a is shown as a ribbon diagram (lavender; drawn with program RIBBONS [Carson 1997]). The superhelical axis of the repetitive part of the molecule is approximately horizontal. The two SV40 NLS peptides are shown in a ball-and-stick representation; the peptide bound to the major site is colored yellow, and the peptide bound to the minor site is colored orange. (b) Structure of Impa(70-529)-nucleoplasmin NLS complex, shown as in (a). The nucleoplasmin NLS peptide is colored cyan.