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Figure 2.
Figure 2. DNA Recognition by c-Myb and AMV v-Myb(A and B)
Schematic representations of DNA recognition by c-Myb (A) and
AMV v-Myb (B). Dashed and solid lines depict intermolecular
hydrogen bonds and van der Waals contacts, respectively. DNA
bases labeled in red are involved in direct interactions with
proteins.(C) Stereo view of specific interactions between c-Myb
and DNA bases. The peptide backbone of c-Myb is drawn as a pink
or blue tube in the R2 and R3 regions, respectively. Thin and
bold dotted lines depict intermolecular hydrogen bonds and van
der Waals interactions, respectively. Water molecules are shown
as red balls.(D and E) Electrostatic surface potential of
DNA-bound c-Myb R1R2R3 viewed from the front (D) and back (E);
positively and negatively charged areas are colored blue and
red, respectively.
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