Figure 2.
Fig. 2. NHERF PDZ1 interactions with the peptide QDTRL.
A, stereo view of a 2F[obs] F[calc]
electron density map calculated at 1.7-Å resolution and
contoured at 1 at the
peptide-binding site. B, stereo image of the NHERF PDZ1 binding
pocket bound to the carboxyl-terminal peptide ligand (gray).
Carbon, oxygen, and nitrogen atoms are shown in black, red, and
blue, respectively. Water molecules are shown as red spheres and
hydrogen bonds as dashed lines. C, two-dimensional
representation of the interactions observed between the NHERF
PDZ1 residues (orange) and the peptide ligand (purple). Dashed
lines denote hydrogen bonds, and numbers indicate hydrogen bond
lengths in Å. Hydrophobic interactions are shown as arcs
with radial spokes. The figure was made using LIGPLOT (40).
F[calc]
electron density map calculated at 1.7-Å resolution and
contoured at 1 
at the
peptide-binding site. B, stereo image of the NHERF PDZ1 binding
pocket bound to the carboxyl-terminal peptide ligand (gray).
Carbon, oxygen, and nitrogen atoms are shown in black, red, and
blue, respectively. Water molecules are shown as red spheres and
hydrogen bonds as dashed lines. C, two-dimensional
representation of the interactions observed between the NHERF
PDZ1 residues (orange) and the peptide ligand (purple). Dashed
lines denote hydrogen bonds, and numbers indicate hydrogen bond
lengths in Å. Hydrophobic interactions are shown as arcs
with radial spokes. The figure was made using LIGPLOT (40).