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Figure 2.
Fig. 2. Superimposition of the ATB17-isovalerate complex
(pink, large domain; gray, small domain) and the wild-type
AspAT-maleate complex (purple). The backbone of one subunit of
ATB17, of which the large domain (residues 49-325) was
superimposed on that of the wild-type AspAT (31), is indicated
by a thick line. The NH[2]- and COOH termini of the subunit are
indicated (N and C). The side chains of the residues that were
mutated in ATB17 are shown as follows: the two clusters of the
residues (see text) are in red and green, and the other residues
are in light blue. The coenzyme, pyridoxal 5'-phosphate
(yellow), and the bound valine analog, isovalerate (dark blue),
are also shown. Maleate of the wild-type AspAT-maleate complex
is omitted. Figs. 2 and 4 were produced with MOLSCRIPT and
RASTER 3D (32-34).
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