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Figure 1.
Figure 1. Comparison of EF-G structures with H573A, T84A
and G16V mutations. (a) Superimposition of the C^a traces from
H573A EF-G (green), T84A (magenta) and G16V (yellow). (b) Zoom
in on the box in (a) showing the significant local differences
in the conformations of switch II and helix B[III]. The colour
scheme is the same as for (a). (c) An all-atom representation of
switch II in the "wild-type" conformation observed in mutant
H573A. The importance of Phe90 and Pro85 for the hydrophobic
core can clearly be seen. In all panels, the GDP molecules are
shown in a ball-and-stick representation with carbon atoms
coloured identically to the C^a traces. The Mg ions are shown as
magenta spheres.
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