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Figure 1.
Figure 1. (a) Stereo view of F[o] -F[c] electron density
map showing inhibitor bound to one subunit of HslV. Phases were
computed from HslUV model that resulted from one cycle of
simulated annealing after all inhibitor atoms were omitted from
the model. Contour levels, 5s (magenta), 12.5s (cyan). The
Figure was prepared with BOBSCRIPT[25.] and RASTER3D. [26.] (b)
Proposed structure of NLVS-HslV covalent complex with Thr1 of
HslV. [14.] Inhibitor atoms and bonds are drawn bold; HslV
atoms/bonds are drawn fine. The S1 and S3 HslV binding pockets
are shown schematically above the moieties they bind.
Orientation of inhibitor is similar to orientation in part (a).
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