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Figure 1.
Fig. 1. a, structure of  3GT with
bound UDP and Mn2+ ion. The bound ligand and ion identify the
location of the active site. The Mn2+ ion is shown as a magenta
sphere, UDP is brown, and helices are pink, while the strands
are green. This image was created using the program MOLSCRIPT
(38). b, the amino acid sequence of the catalytic domain of 3GT with
all secondary structure elements highlighted. UDP binding
residues are marked in yellow, while the Mn2+ binding residues
are shown by closed magenta spheres. This image was created
using the program ALSCRIPT (39). c, stereoview comparison of the
C^  atoms
of form-II 3GT
(present structure, in red) with the previously determined form
I 3GT
structure (Ref. 18; in black). The C-terminal residues 358-368
in form II show a large difference in conformation and form a
lid for the active site tunnel. This image was created using the
program BOBSCRIPT (40).
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