Figure 7 - full size

Figure 7.
FIGURE 7. Comparative C and T base pairing orientations opposite O^6-MeG at the catalytic center of the ternary complexes. A, the 14th nucleotide C forms a wobble base pair with template O^6-MeG in the O^6-MeG:C structure. B, the 14th nucleotide T is positioned in three conformations opposite O^6-MeG, owing to the disorder observed in the region near thymidine in the O^6-MeG:T structure. The electron density map (black mesh) 3F[o] - 2F[c] is contoured at the 1 level.