Figure 7 - full size

Figure 7.
Fig. 7. Schematic diagram of the NLS-dependent nuclear import pathway. Yellow, importin- ; green, importin- ; cyan, NLS-containing cargo protein; magenta, Ran-GTP. For simplicity, other factors involved in the pathway such as nuclear transport factor-2, the nuclear export receptor for importin- , and Ran-binding proteins have been omitted from the diagram. Dissociation constants for the different binding events are shown.