Figure 6.
Figure 6 Stereo diagrams of the CDR1 and CDR3 loops in the two
conformational isomers of the Sea dimer. CDR1 is yellow in
monomer A (L-type isomer) and blue in monomer B (H-chain
analog). CDR3 is magenta in monomer A and red in monomer B.
Hydrogen bonds between CDR1 and CDR3 are designated by dotted
lines and the interatomic distances in Å between backbone
carbonyl and amide groups are superimposed. Short stretches of
antiparallel -strand
pairing occur between the descending arm of the CDR1 loop and
the ascending arm of CDR3 in both monomers. Otherwise, the
conformations of the CDR1 and CDR3 loops are substantially
different in the two isomers. The models were drawn with the
program MOLSCRIPT (Kraulis, 1991[Kraulis, P. J. (1991). J. Appl.
Cryst. 24, 946-950.]).
-strand
pairing occur between the descending arm of the CDR1 loop and
the ascending arm of CDR3 in both monomers. Otherwise, the
conformations of the CDR1 and CDR3 loops are substantially
different in the two isomers. The models were drawn with the
program MOLSCRIPT (Kraulis, 1991[Kraulis, P. J. (1991). J. Appl.
Cryst. 24, 946-950.]).