Figure 5.
Figure 5: Recognition of the DELLA domain by GID1A. a, A top
view of the GID1A core domain (light blue) and the N-terminal
extension (cyan) with the GAI DELLA domain (pink). The view
corresponds to Fig. 2b, d. b, A close-up view of the thumb helix
A
hooked onto the GID1A crevice. Residues of the DELLA motif
(residues D28–V38) are highlighted in green. Hydrogen bonds
are indicated with dotted lines. A bridging water molecule
inside the loop is shown as a red sphere. c, The LExLE motif
(M43–M57). d, The VHYNP motif (T72–M87). In b–d, the
residues in each motif that directly contact GID1A are
highlighted in green.
A
hooked onto the GID1A crevice. Residues of the DELLA motif
(residues D28–V38) are highlighted in green. Hydrogen bonds
are indicated with dotted lines. A bridging water molecule
inside the loop is shown as a red sphere. c, The LExLE motif
(M43–M57). d, The VHYNP motif (T72–M87). In b–d, the
residues in each motif that directly contact GID1A are
highlighted in green.