Figure 5.
Fig. 5. The copper ions bound at His^99 and His^41
displayed as blue spheres surrounded by electron density of the
anomalous Fourier map in red (contour 5 ) in stereo. His^57 has
the capacity for liganding Cu1 and Cu2 by a side chain rotation
(His57*), requiring shifts of the ions, whereas the mutant H99A
proves that only the His^99 site is the structural basis for the
Zn^2+ and Cu^2+ inhibition of hK7.
) in stereo. His^57 has
the capacity for liganding Cu1 and Cu2 by a side chain rotation
(His57*), requiring shifts of the ions, whereas the mutant H99A
proves that only the His^99 site is the structural basis for the
Zn^2+ and Cu^2+ inhibition of hK7.