Figure 5 - full size

Figure 5.
Figure 5 Detailed interaction between me2K4 in H3K4me2 and Glu322 in WDR5. (A) The H3K4me2 peptide and WDR5 are colored in yellow and blue, respectively. The electron density map is contoured at 1 . Potential water-mediated hydrogen bonds are shown as dashed orange lines. (B) The lower panel shows schematics of two alternative hydrogen binding networks involving the water molecule.