Figure 7 - full size

Figure 7.
Figure 7. Suggested LRP recognition motif. (a) Schematic representation of the four residues D/E-K-W-Ψ interaction motif. Ψ is a hydrophobic residue or a residue with a significant non-polar part. (b)–(d) Views of the identified motifs in (b) LRP–RAP represented by the present HADDOCK model for CR56–RAPd1, (c) the structure of VLDLR in complex with the human rhinovirus (PDB accession code 1N7D) and (d) the low pH structure of LDL with interactions between LB5 and the β-propeller (PDB accession code 19VU).