Figure 5 - full size

Figure 5.
Figure 5. Surface representation of B-box1 showing basic patches (colored blue) comprised of lysine and arginine residues, acidic patches of glutamic and aspartic acids (colored red), and hydrophobic surfaces (colored green) formed by leucine, isoleucine, alanine, phenylalanine, and valine residues. The red arrow indicates a cleft formed by two acidic residues flanking a hydrophobic pocket. The blue arrow indicates a large cleft of basic residues that may be important for protein–protein interaction (possibly with Alpha 4).