Figure 5 - full size

Figure 5.
Fig. 5. Superposition of the binding site of 1934-human HA in its uncomplexed state and complexed with avian receptor analog. The HA is shown in green in both cases, and the avian receptor is colored as in Fig. 3. Two water molecules, shown as green spheres, link Glu190 to Gln226 in the avian receptor complex. This hydrogen-bonded network is not formed in the uncomplexed structure or in the human receptor complex not shown.