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Figure 5.
Figure 5 Changed solvent structure in H3 Arg-116 mutants. (A)
The 'van der Waals cup' formed by H3 Met-120, Pro-121, and
Lys-122, holding the chloride ion. 2Fo-Fc electron density,
contoured at 1 sigma, is shown in gold. (B) The same region is
shown for H3 Arg-116-His (blue). Note the missing density for
the chloride ion. (C) In H3 Arg-116-Ala, minor density is
observed for the chloride ion, indicating only partial
occupancy. (D) Superposition of the three structures, viewed
from above with respect to the views shown in (A -C). Wild type
is shown in wheat, and mutants in blue. The chloride ion is
omitted for clarity.
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