Figure 5 - full size

Figure 5.
Figure 5. Comparison of the Dbs -RhoA, Dbs -Cdc42 and Tiam1 -Rac1 structures. a, Interface of the DH domain of Dbs (yellow) and Cdc42 (green). b, Interface of the DH domain of Dbs and RhoA (green). c, Superposition of the backbone traces of the 4/ 5 loop of ITSN and Tiam1 on the Dbs -RhoA complex. ITSN (blue) and Tiam1 (red) backbones are semitransparent, and Dbs is yellow. d, Interface of the DH domain of Tiam1 (yellow) and Rac1 (green). Unless otherwise noted, coloring is according to the styles used in Fig. 3.