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Figure 4.
Figure 4. Non-desensitizing glutamate receptors created by
ligand-binding core disulfide bond cross-links. Responses to
10 mM glutamate, recorded from outside-out patches from HEK
cells transfected with the indicated cDNA species, are shown for
wild-type GluR2 and the kainate receptors GluR5, GluR6 and GluR7
(left charts) and for their ligand-binding core double cysteine
mutants (right charts). Upper traces in each panel show open-tip
responses recorded at the end of the experiment.
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