Figure 4 - full size

Figure 4.
Figure 4: Orientation of the myoV-inhibited structure on F-actin. F-actin strands rendered light blue and grey. Actin docking is based on ref. 30. a, Panel shows F-actin can bind only one myoV head at a time. The unbound head extends up towards the viewer. b, Same view direction as a but with the second head docked. c, High-magnification gallery of actin-bound myoV molecules. In some the S2 domain can be seen between the two heads. Drying in negative stain would flatten the structure onto a plane, which may account for some of the differences between the models and the micrographs.