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Figure 4.
Fig. 4. Comparison of the reduced and oxidized forms of
mMICAL[489].(A and B) Superposition of the two forms. The FAD
molecules are drawn as balls and sticks (carbons of oxidized
mMICAL[489], cyan; carbons of reduced mMICAL[489], orange). The
main chain of the oxidized form is depicted as a ribbon. B is
rotated by 90° about the x axis relative to A. (C and D)
Coordination of the isoalloxazine ring in the oxidized (C) and
reduced (D) forms viewed from a common orientation. The
isoalloxazine ring and selected residues are depicted as sticks
(orange, carbon of reduced isoalloxazine; gray, protein carbon),
waters are shown as spheres, and H bonds are shown as yellow
dashes.
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