Figure 4.
FIG. 4. The atoms are colored as gray, blue, red, and
yellow for carbon, nitrogen, oxygen, and phosphor, respectively
and panels a and b were produced using Quanta. a, stereo view of
electron density (2F[o] - F[c] coefficients, 1.0 level)
for AMP-PNP with two bound magnesium ions. b, the binding
interactions of AMP-PNP phosphates with Pim-1. Lys169 does not
bind AMP-PNP in Pim-1, contrasting with what is observed in
other kinases. Single letter amino acid abbreviations are used
with position numbers.
level)
for AMP-PNP with two bound magnesium ions. b, the binding
interactions of AMP-PNP phosphates with Pim-1. Lys169 does not
bind AMP-PNP in Pim-1, contrasting with what is observed in
other kinases. Single letter amino acid abbreviations are used
with position numbers.