Figure 4 - full size

Figure 4.
Figure 4. Details of the Interactions between the Aggrecan CLD and TN3–5
Important interacting side chains are shown as ball-and-stick, and the central hydrogen bonds are highlighted. The color scheme is as described in the legend to Figure 2.
(A) Molecular interactions of the hydrophobic patch on loop L4 of the aggrecan CLD. The view is approximately the same as in Figure 2A.
(B) Interactions involving the CC′ loop in TN4. The view is approximately as in (A).
(C) Interactions of the TN4–5 linker region and the FG loop on TN5. The molecule has been rotated by approximately 180° around a vertical axis to make the interactions clearer; i.e., the view is from the back of the molecule as seen in Figure 2A.