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Figure 4.
Figure 4. The cis-syn thymine dimer base pairs with ddATP in the
closed CPD-5'b complex. (a) View from the major groove side
of the duplex DNA. (b) The view in a has been rotated by 90°
along an axis (straight arrow). The 3' T of the CPD forms a
normal Watson-Crick base pair with the 3' base of the primer. A
twisted base pair is formed between the 5' T and the incoming
ddATP. The view in b shows the distorted stacking of the 5' T
base pair with that of the 3' T. The nucleic acids are in
ball-and-stick representation with the same color scheme used in
Figure 1.
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