Figure 4 - full size

Figure 4.
Figure 4. Superimposition of Pol λ with the Open and Closed Conformations of Pol βSuperimposition of the α carbon trace of human Pol λ (red) with the structures of human Pol β in an open (1BPX; yellow) and closed (1BPY; blue) conformation. The roman numerals refer to different regions of the Pol λ structure as indicated in the text. The rms deviation was 1.4 Å for 112 C-α atoms for 1BPX and 1.4 Å for 113 C-α atoms for 1BPY.