Figure 4 - full size

Figure 4.
Fig. 4. Interactions between 2 and PTP1B. a, H-bonding (blue dotted lines) and polar interactions (red dotted lines); b, hydrophobic interactions (orange dotted lines), and; c, interactions between the two fluorine atoms in F[2]Pmp and PTP1B. The cut-off distance used is 3.2 Å for hydrogen bonds, 4.0 Å for electrostatic or polar interactions, and 4.5 Å for hydrophobic interactions.