Figure 4 - full size

Figure 4.
Fig. 4. Derivatives of the antirhinoviral drug AG7088 should inhibit coronavirus Mpros. A superimposition (stereo image) of the substrate-binding regions of TGEV Mpro (marine) in complex with the hexapeptidyl CMK inhibitor (red) and HRV2 3C^pro (green) in complex with the inhibitor AG7088 (yellow) is shown.