Figure 4 - full size

Figure 4.
Figure 4. Detailed diagram illustrating AlF[3] binding in the active site region of the ADP-Mg2+-AlF[3] E. coli PCK quaternary complex. Note that the fluorine atoms interact primarily with basic residues or Mg2+. The aluminum atom is close to an oxygen atom of the b-phosphoryl group of ATP. Mg2+ is the light blue sphere, the aluminum atom is colored pink, the fluorine atoms are colored green. (a) PCK-ADP-AlF[3]-Mg2+ complex (complex I). (b) PCK-ADP-AlF[3]-Mg2+-pyruvate complex (complex II).