Figure 4 - full size

Figure 4.
Figure 4 Final 2F[o]-F[c] stereoplot at a 1 contour level of a region showing the hydrophobic cavity with (A) the A-strand as in the M-ECAD12 structure and (B) the free tryptophan as in the M-ECAD12+W structure. Continuous density (green) is observed for the A-strand (red), with chain tracing being unambiguous (A), whereas it could only be traced from Ile4 in (B); additional density in the hydrophobic pocket was interpreted as a free tryptophan. The figure was prepared with DINO (Phillipsen, 1998).