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Figure 4.
Fig. 4. Protein-carbohydrate interactions. The molecular
surface (colored according to charge) for the Fab fragment of
S-20-4 with the (a) monosaccharide and (b) disaccharide ligands.
(c) Close view of the bound monosaccharide, with the sugar ring
facing a central hydrophobic pocket and the tetronic acid moiety
occupying a shallow cavity formed by residues from the Ab heavy
chain. (d) Intermolecular hydrogen bonding interactions in the
Fab-disaccharide complex. [The hydrogen bond between the
carbonyl group of the upstream terminal sugar residue (arrow)
and the main chain NH group at position H98 is not shown.]
Figure produced with the program GRASP (41).
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