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Figure 3.
Overview of the complex structure. (A) Schematic
representation of the ^8–9FnI module pair in gold and the
α[1](I) G[778]–G[799] peptide in cyan showing the
antiparallel β-strand mode of binding. (B) Similar
representation of ^2–3FnI (purple) in complex with a peptide
(gold) from Staphylococcus aureus (21). Collagen and bacterial
peptides adopt a similar model of binding to FnI domains. (C)
Molecular surface area representation of ^8–9FnI colored by
electrostatic potential and select collagen peptides residues
involved in complex formation.
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