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Figure 3.
A symmetric complex is formed between cIAP2 RING dimers and
UbcH5b. A, schematic representation of the crystal structure of
cIAP2 RING domain (bright green) bound to UbcH5b (brown). The
complex is symmetrical around the RING domain dimer interface,
with one RING and one UbcH5b per asymmetric unit. B, comparison
of the cIAP2 RING domain dimer (light green) with the cIAP2
RING-dimer from the complex structure (bright green). The RING
domains were overlaid using secondary structure matching. C,
close up view of the C terminus from free and E2-bound cIAP2
RING.
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