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Figure 3.
Fig. 3. CTE binding to the bottom face of the -propeller. (A) The
surface of the Nup214 -propeller is colored
according to the electrostatic potential from –10 k[B]T (red)
to + 10 k[B]T (blue). The CTE is shown in blue coil
representation with the side chains in ball-and-stick
representation. The black box indicates the region magnified in
D. (B) Hydrophobic interactions of CTE residues Val-410,
Leu-413, and Leu-414 (yellow). (C) Interactions of Leu-420 and
Leu-422 (yellow) with residues of the -propeller. Hydrophobic
pocket-forming residues are shown in gray. The surface of the
-propeller is colored as
in A. (D) Schematic representation of the contacts between the
-propeller and the CTE.
Hydrogen and ionic bonds are indicated by orange dashed lines
and van der Waals contacts with gray grooves.
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