|
Figure 3.
Figure 3. Crystal Structures of Ligands 1 and 4 Bound in
Active and Inactive CDK2
(A–C) The overlay shown is
residues 77–143 of the same inhibitor (yellow, active; blue,
inactive) and with the substituted aniline derivative 4 (yellow)
bound in (B) monomeric CDK2 (green) and (C) active (pink) CDK2.
|
