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Figure 3.
Figure 3. Electrostatic surface potential and conservation
of surface residues of mTREM-1. Left: the surfaces and
electrostatic potentials were generated in INSIGHTII (Molecular
Simulations, Inc., San Diego, CA). Positive potential (>=10 mV)
is blue, neutral potential (0 mV) is white and negative
potential ( -10 mV) is red. CDR-equivalent regions are marked by
an oval. Right: Accessible surface area representation and
ribbon diagram of the mTREM-1 Ig domain was generated using
PyMOL (http://pymol.sourceforge.net/). Residues with 100%
identity between the human, mouse, cow and pig TREM-1 sequences
are colored green. The "Front" orientation is equivalent to that
of Figure 1(a).
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