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Figure 3.
Figure 3. The N-src loop of nephrocystin SH3 is twisted by a
noncanonical proline residue. Stereo view of the superimposed
backbones of nephrocystin (green) and N-Crk SH3 (yellow; PDB
entry: 1CKA). The two structures are very similar, with the
exception of the N-Src loop, at the right. Proline 186, which
induces a kink in nephrocystin, is shown in red. It corresponds
to a position where a semiconserved Glu, Asp, or Asn residue is
found in most SH3 domains.
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