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Figure 3.
FIG. 3. Overall structures of the PDZ dimer. A, Shank1 PDZ
dimer. The black arrow indicates the N-terminal end of each
peptide ligand. B, ribbon diagram of the GRIP PDZ6 dimer
(Protein Data Bank code 1N7F [PDB]
). C, Shank PDZ dimer interface. Side chains of hydrophobic
residues at the interface are shown as ball and stick models. D,
amino acid sequence and predicted secondary structure of the
C-terminal domain of  PIX. The secondary
structure was predicted using the PredictProtein Web server
(cubic.bioc.columbia.edu/predictprotein/). E, proposed model of
the Shank1 PDZ and PIX C terminus complex.
The figures were made using PyMOL (www.pymol.org).
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