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Figure 3.
Fig. 3. Diagram of the active-site structure of TM-3
complexed with pENW. (A) The overall active-site structure.
Proteinase molecule is represented by the solid surface-charge
potential. The pENW, a cadmium ion and its ligated water
molecule in the active site are denoted by a stick model and
various spheres in cyan, yellow and magenta, respectively. The
Cd-coordinated histidines and neighboring glutamyl residue are
colored in magenta. Residues surrounding the active-site pocket
are labeled. Diameters of the pocket corresponding to the S^-1
site of TM-3 are indicated in Å. (B) A skeletal
representation. The active-site structure of the pENW-bound TM-3
is shown with a stick model. Residues surrounding the
hydrophobic substrate binding pocket are in yellow, while those
locating at bottom are in green. The possible hydrogen bonds are
shown. Both figures were prepared using grasp.
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