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Figure 3.
Figure 3. Comparison of the architectures of the
metallo-hydrolases having disordered (a/b)[8] barrels. (a)
Arrangement of b-strands composing the barrels. Corresponding
main-chain atoms of the b-strands are superimposed by
least-squares fitting. The strands of subunit A of the hrDP are
shown as yellow arrows; urease in sky-blue, phosphotriesterase
in orange, and adenosine deaminase in red. The strands labeled
b1 through b8 are sequentially arranged from the N-terminal side
in each polypeptide. (b) Superimposition of the metal ions and
ligands through least-squares fitting. The metal ions and ligand
groups of the hrDP subunit A are drawn in yellow, urease in
sky-blue, and phosphotriesterase in orange. Carbamoyllysine
ligands are represented with Carb-K labels. The fittings in (a)
and (b) were calculated independently.
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