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Figure 3.
Figure 3: Structure of CaM lobes in the CaMBD/Ca^2+/CaM complex.
a, Left, C  superimposition
of N-lobe residues 10 -67 of the CaMBD/Ca^2+/CaM complex (blue)
onto those of the Ca^2+/CaM complex12 (yellow). Ca^2+ ions are
shown as spheres. Right, C superimposition
of C-lobe residues 81 -146 of the CaMBD/Ca^2+/CaM complex (blue)
and the NMR apoCaM C-lobe structure^15 (magenta) onto that of
the Ca^2+/CaM complex12 (yellow). b, Comparison of the C-lobe EF
hand regions of the Ca^2+/CaM12 and the CaMBD/Ca^2+/CaM
complexes. Ca^2+-coordinating residues are shown as sticks. Note
the displacements of Ca^2+-coordinating residues Asp 95, Asp
131, Glu 104 and Glu 140 out of the expanded Ca^2+-coordination
sphere in the CaMBD complex.
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