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Figure 2.
Figure 2: Sp-cAMPS induced conformational changes. a,
Superposition of the active and inactive second CNB domain. The
arrows indicate the movement of the hinge and the lid region.
Light green, active conformation; dark green, inactive
conformation; grey, no difference in conformation. b,
Interactions of Sp-cAMPS with the CNB domain and the REM domain.
Hydrogen bonds are shown by dotted lines; w, water. c,
Interaction of Lys 405 with the hinge-lid region.
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