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Figure 2.
Figure 2 The post-rigor state of myosin VI. (A) The myosin VI
post-rigor structure is compared to that in the rigor-like state
(right). The motors are oriented as if they are bound to a
vertical actin filament (black arrow). Note the position of the
lever arm, which is very similar in the rigor-like and
post-rigor states. (B) On the left, porcine myosin VI in the
post-rigor state (red) is compared with the myosin VI rigor-like
state (black) after superposition of the L50 subdomains. Note
the difference in the position of the Nter and U50 subdomains.
The actin-binding cleft is more open in the post-rigor state
(red) compared with the rigor-like state (black). On the right,
three different post-rigor state structures are superimposed
(chicken myosin V in black, Dictyostelium myosin II in gray and
porcine myosin VI in red). Note that the positions of their
subdomains are quite similar.
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