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Figure 2.
FIGURE 2. Overall structure of ZO1-PDZ1. A,
crystallographic dimer of ZO1-PDZ1-YL with the PDZ domains
colored red and magenta and the heptapeptide ligands colored
green. Regions in gray represent the tri-glycine linker between
the PDZ domain and the ligand and a tetrapeptide that was fused
to the N terminus as a result of the cloning procedures. B,
stereoscopic representation of ZO1-PDZ1-YL with secondary
structure elements labeled (PDZ domain, gray; heptapeptide,
green). Structural figures were produced with PyMOL (DeLano
Scientific, San Carlos, CA).
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