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Figure 2.
Figure 2. A: A stereo diagram showing the overall APC35832
structure. B: Superimposition of APC35832 and the Toprim domain
of T7 DNA primase (PDB entry 1NUI), showing conserved acidic
residue positions. APC35832 is colored pink, 1NUI is blue and
conserved acidic residues are highlighted in green and yellow.
C: The solvent-accessible surface colored according to
electrostatic potential (blue positive, red negative, calculated
with DS ViewerPro 6.0 [Accelerys Software]). The acidic surface
pocket is visible, with the MES molecule shown as sticks.
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