Figure 2.
Figure 2 Structure of Chk2 kinase domain. Secondary structure
cartoon of the binary complex of CHK2-KD with ADP. The
glycine-rich loop is coloured pink, the DFG and APE motifs red,
and the T-loop yellow. Secondary structure elements
corresponding to -strands
are coloured blue and -helices
cyan. ADP is shown as a 'stick' model. The catalytic residue
Asp347, conserved residues Lys249 and Glu373, and
autophosphorylation sites Thr383 and Thr387 are also
highlighted. Molecular images in this and subsequent figures
were generated using PyMOL (www.pymol.org).
-strands
are coloured blue and 
-helices
cyan. ADP is shown as a 'stick' model. The catalytic residue
Asp347, conserved residues Lys249 and Glu373, and
autophosphorylation sites Thr383 and Thr387 are also
highlighted. Molecular images in this and subsequent figures
were generated using PyMOL (www.pymol.org).