Figure 2.
Figure 2 Protein -DNA contacts. (A) A schematic view with
ribbons drawn through the C s
of the Tc3A DNA-binding domain (yellow) and through the
phosphate backbone of the DNA strands (blue and magenta). (B)
Sketch summarizing the hydrogen bonding (indicated by green
dotted lines, base-specific H-bonds by green solid lines) and
salt bridging contacts (blue lines) between the Tc3A domain and
the DNA. Gray boxes indicate residues involved in base-specific
contacts. Hydrogen bonds are at a maximum distance of 3.5 Å and
salt bridges at a maximum of 4.0 Å (Barlow and Thorton, 1983).
(C) and (D) Stereo views (Kraulis, 1991) of the HTH DNA contacts
in the major groove, and the N-terminus of Tc3A bound in the
minor groove of DNA, respectively. Hydrogen bonds are indicated
with green dotted lines.
s
of the Tc3A DNA-binding domain (yellow) and through the
phosphate backbone of the DNA strands (blue and magenta). (B)
Sketch summarizing the hydrogen bonding (indicated by green
dotted lines, base-specific H-bonds by green solid lines) and
salt bridging contacts (blue lines) between the Tc3A domain and
the DNA. Gray boxes indicate residues involved in base-specific
contacts. Hydrogen bonds are at a maximum distance of 3.5 Å and
salt bridges at a maximum of 4.0 Å (Barlow and Thorton, 1983).
(C) and (D) Stereo views (Kraulis, 1991) of the HTH DNA contacts
in the major groove, and the N-terminus of Tc3A bound in the
minor groove of DNA, respectively. Hydrogen bonds are indicated
with green dotted lines.