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Figure 2.
Figure 2. Oligosaccharides used in structural studies of DC-SIGN
and DC-SIGNR. Symbols are as defined in Figure 1. Structures
of the complexes of both proteins with the GlcNAc[2]Man[3]
oligosaccharide are as described^14. This oligosaccharide
contains a branch mannose that is not linked to other sugars.
The branch mannose residues in the high-mannose oligosaccharide
are linked in either (outer
branch) or (core
branch) configuration. The Man[4] oligosaccharide is an analog
of the outer branch structure.
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