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Figure 2.
Fig. 2. The domain II/IV contact. (A) Side chains of residues
that mediate contacts between domain II (green) and domain IV
(red) are shown. Hydrogen bonds and salt bridges are indicated
by dashed lines. This figure was made with MOLSCRIPT (36). (B)
Alignment of human ErbB receptor sequences from the domain II/IV
contact regions. Residues with direct contacts to one another in
sHER3 are highlighted in similar colors. Pro593 and Phe^595 of
HER2, which fail to conserve the pattern of contact residues,
are underlined.
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