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Figure 2.
Figure 2. A new allosteric binding pocket for compound 1 in
human p38 MAP kinase. a, Schematic drawing of the structure
of p38 MAP kinase in complex with compound 1. The inhibitor is
shown as a stick model, with carbon atoms in green. The expected
location of the ATP molecule^8 (purple for carbon atoms) is
shown for reference. b, Final 2F[o] - F[c] electron density map
for compound 1, contoured at 1  level.
Panel (a) is produced with RIBBONS27 and panel (b) with SETOR28.
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